To run gemma-4-21b-a4b-it-REAP-GGUF locally at Q8_0 quantization, you need at minimum 24.65 GB of GPU VRAM.
Dual-GPU via tensor parallelism. Best cost per GB at this tier.
Single-card 48GB pro GPU. Clean setup, no multi-GPU overhead.
Data-centre HBM2e bandwidth. Dramatically faster throughput.
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